Agarose-microeneapsulated Islet Xenotransplantation.
نویسندگان
چکیده
منابع مشابه
Clinical Islet Xenotransplantation
Type 1 diabetes (T1D) is a major health problem throughout the world. In the U.S., it is estimated that about 1.5 million people suffer from T1D. Even when well controlled—by frequent monitoring of blood glucose and administration of insulin, the long-term complications of the disease are significant and include cardiovascular disease, nephropathy, retinopathy, and neuropathy (1). Here we revie...
متن کاملPiscine islet xenotransplantation.
Tilapia, a teleost fish species with large anatomically discrete islet organs (Brockmann bodies; BBs) that can be easily harvested without expensive and fickle islet isolation procedures, make an excellent donor species for experimental islet xenotransplantation research. When transplanted into streptozotocin-diabetic nude or severe combined immunodeficient mice, BBs provide long-term normoglyc...
متن کاملClinical Islet Xenotransplantation: A Step Forward
Article history: Received 21 September 2016 Accepted 21 September 2016 Available online 24 September 2016 (n= 4) or 10,000 IEq/kg × 2 (n= 4) of encapsulated neonatal porcine islets in their peritoneal cavity by laparoscopy. Although the study demonstrated significant improvement in HbA1c and reduction of hypoglycemic unawareness events with an improved transplant estimated function (TEF) score ...
متن کاملPotential for clinical pancreatic islet xenotransplantation
License. The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. Permissions beyond the scope of the License are administered by Dove Medical Press Limited. Information on how to request permission may be f...
متن کاملPig-to-Nonhuman Primates Pancreatic Islet Xenotransplantation: An Overview
The therapy of type 1 diabetes is an open challenging problem. The restoration of normoglycemia and insulin independence in immunosuppressed type 1 diabetic recipients of islet allotransplantation has shown the potential of a cell-based diabetes therapy. Even if successful, this approach poses a problem of scarce tissue supply. Xenotransplantation can be the answer to this limited donor availab...
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ژورنال
عنوان ژورنال: The Japanese Journal of Gastroenterological Surgery
سال: 1996
ISSN: 0386-9768,1348-9372
DOI: 10.5833/jjgs.29.911